Bioinformatics/neuroinformatics student stipends

Reliable interpretation of genomic and neurological information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). The Statomics Lab seeks graduate students who will conduct original research involving the application of novel statistical tools to the analysis of transcriptomics, proteomics, metabolomics, genome-wide-association data, and/or neuroscience data.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Strong self motivation and good communication skills are also absolutely necessary. The following qualities are desirable but not required: coursework in bioinformatics, computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To be considered, send a PDF CV that has your GPA and contact information of two references to dbickel@uOttawa.ca with the degree sought (either MSc or PhD) and the preferred graduate program (either Biochemistry or Mathematics and Statistics) in the Subject line of the message and with a cover letter in the body of the message. Only those students selected for further consideration will receive a response.

Computational biostatistics student stipends

Reliable interpretation of genomic information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). The Statomics Lab seeks students who will conduct original research involving the application of novel statistical methods to the analysis transcriptomics, proteomics, metabolomics, and/or genome-wide-association data while earning a graduate degree in Mathematics and Statistics. For information on careers in statistics, see http://tiny.cc/Rqvnf and http://amstat.org/careers/.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Strong self motivation, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To be considered, send a PDF CV that has your GPA and contact information of two references to dbickel@uOttawa.ca with the degree sought (MSc or PhD) in the Subject line of the message and with a cover letter in the body of the message. Only those students selected for further consideration will receive a response.

Postdoctoral training in statistical bioinformatics

Reliable interpretation of genomic and neurological information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). The Statomics Lab seeks a postdoctoral fellow who will collaboratively develop and apply novel methods of statistical inference to attack current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, genome-wide-association data, and/or neuroscience data.

A thorough knowledge of computationally intensive statistics is essential, as is the ability to quickly develop reliable software implementing the statistical algorithms developed. Strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field within four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: expertise in bootstrapping and/or constructing accurate confidence intervals; a working knowledge of biology; familiarly with R, S-PLUS, Mathematica, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel@uOttawa.ca, with “Postdoctoral Fellowship” and the year of your graduation or anticipated graduation in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

Research Associate in statistical bioinformatics

Reliable interpretation of genomic and neurological information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). The Statomics Lab seeks a Research Associate who will collaboratively develop and apply novel methods of statistical inference to attack current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, genome-wide-association data, and/or neuroscience data. The successful candidate will also play a key role in the mentorship of junior members of the lab.

A thorough knowledge of computationally intensive statistics is essential, as is the ability to quickly develop reliable software implementing the statistical algorithms developed. A promising publication record, strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: expertise in bootstrapping and/or constructing accurate confidence intervals; a working knowledge of biology; familiarly with R, S-PLUS, Mathematica, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel@uOttawa.ca, with “Research Associate” in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

Significance v. fold change

C. M. Yanofsky and D. R. Bickel, “Validation of differential gene expression algorithms: Application comparing fold change estimation to hypothesis testing,” BMC Bioinformatics 11, 63 (2010). Article

Subjective frequentism

D. R. Bickel, “A frequentist framework of inductive reasoning,” arXiv:math.ST/0602377 (2009). Full preprint

Merry Christmas!

Observed confidence levels

Alan Polansky not only enjoys railroads, but also announces news on attained confidence levels.

Career prospects for statisticians

Careers in Mathematics and Statistics

What Do Statisticians Do?

Empirical null conditioning

D. R. Bickel, “Estimating the null distribution for conditional inference and genome-scale screening,” Technical Report, Ottawa Institute of Systems Biology, arXiv.org:0910.0745 (2009). Full preprint

Graduate studies in statistical lipidomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). For the CIHR Training Program in Neurodegenerative Lipidomics, the Statomics Lab seeks a graduate student who will develop novel methods of statistical inference and collaboratively use them to discover or validate changes in lipid concentration.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Strong self motivation, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To be considered, send a PDF CV that has your GPA and contact information of two references to dbickel0@uottawa.ca (without the zero) with “statistical lipidomics graduate student” in the Subject line of the message. In the message body, specify the graduate program in which you wish to take courses (either Biochemistry or Mathematics and Statistics) and the degree sought (MSc or PhD). Only those students selected for further consideration will receive a response.