Graduate studies in statistical lipidomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statomics Lab of the Ottawa Institute of Systems Biology (http://www.statomics.com). For the CIHR Training Program in Neurodegenerative Lipidomics, the Statomics Lab seeks a graduate student who will develop novel methods of statistical inference and collaboratively use them to discover or validate changes in lipid concentration.

Intellectual curiosity and high mathematical aptitude are essential, as is the ability to quickly code and debug computer programs. Strong self motivation, good communication skills, and a degree in bioinformatics, computer science, mathematics, physics, statistics, any field of engineering, or an equally quantitative field are also absolutely necessary. The following qualities are desirable but not required: coursework in computer science, numerical methods, numerical analysis, software engineering, statistics, and/or biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience with UNIX or Linux.

To be considered, send a PDF CV that has your GPA and contact information of two references to dbickel0@uottawa.ca (without the zero) with “statistical lipidomics graduate student” in the Subject line of the message. In the message body, specify the graduate program in which you wish to take courses (either Biochemistry or Mathematics and Statistics) and the degree sought (MSc or PhD). Only those students selected for further consideration will receive a response.

Postdoctoral training in Bayesian genomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for innovations in statistical methodology and its application to biological systems. This unique opportunity drives research at the Statistical Inference and Computation in Genomics Laboratory of the Ottawa Institute of Systems Biology. The Statomics Lab (http://www.statomics.com) seeks a postdoctoral fellow who will collaboratively develop and apply Bayesian methods of statistical inference to attack current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, and/or genome-wide association data.

A thorough knowledge of Bayesian theory is essential, as is the ability to quickly develop reliable software for approximating posterior distributions using complex models. Strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in biostatistics, statistics, or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: expertise in one or more methods of frequentist inference; a working knowledge of biology; familiarly with R, S-PLUS, Mathematica, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “Bayesian Genomics” and the year of your graduation or anticipated graduation in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

Postdoctoral training in model selection & applications

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for advances in statistical methodology. As the complexity of genomic data sets drives innovative research in statistics, the Statistical Inference and Computation in Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology attacks inferential challenges of importance to human health. The lab seeks a postdoctoral researcher who will collaboratively develop and apply statistical methods of model selection to solve current problems in analyzing transcriptomics, proteomics, metabolomics, lipidomics, and/or SNP-chip data.

A thorough knowledge of statistical theory is essential, as is the demonstrated ability to quickly and accurately implement complex statistical methods in software. Strong initiative, excellent communication skills, and reception of a PhD or equivalent doctorate in biostatistics, statistics, or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: expertise in one or more methods of frequentist model selection; knowledge of biology; familiarly with R, S-PLUS, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “model selection & applications” and the year of your graduation or anticipated graduation in the subject field of the message. In the message body, concisely present evidence that you meet each requirement for the position and describe your most significant papers and software packages with summaries of how you contributed to them. All applicants are thanked in advance; only those selected for further consideration will receive a response.

Bioinformatics graduate program

Ottawa-Carleton MSc/MCI Program in Bioinformatics

David Bickel is currently accepting new students.

For more information on the field of bioinformatics, see the slides from the First Canadian Workshop on Statistical Genomics, the links provided by Georgia Tech, and the jobs posted at the Canadian Bioinformatics Workshops.

Postdoctoral Training in Statistical Genomics

Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for contemporaneous advances in computation and mathematical modeling. As the complexity of genomic data sets drives innovative statistics research, the new Statistical Inference and Computation in Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology seeks a postdoctoral researcher who will collaboratively develop and apply statistical methods to solve current problems in analyzing and integrating gene-expression, proteomics, metabolomics, SNP, ChIP-chip, and/or clinical data. The lab is presently targeting inference in genome-wide association studies, bias reduction in estimated levels of gene expression, and validation of microarray predictions and will attack similar statistical and computational challenges of importance to genetics and functional genomics. The researcher’s background will complement that of any students and any postdoctoral researcher to be recruited to the Statomics Lab from the biomedical and computer science communities, creating an interdisciplinary environment for high impact on the biological sciences as well as on statistics.

Scientific creativity and a thorough knowledge of either Bayesian statistics or another likelihood-based inferential framework are essential, as is the demonstrated ability to quickly and accurately implement likelihood-based methods in software. Strong initiative, excellent communication skills, and reception of a PhD in statistics or a closely related field within the four years prior to the start date are also absolutely necessary. The following qualities are desirable but not required: exposure to the law of likelihood; knowledge of biology; familiarly with BUGS, R, S-PLUS, C, Fortran, and/or LaTeX; experience in a UNIX or Linux environment.

To apply, send a PDF CV that has contact information of three references to dbickel0@uottawa.ca (without the zero), with “likelihood postdoc” and the year of your graduation or anticipated graduation in the Subject line of the message; in the plaintext message body, concisely include evidence that you meet each requirement for the position and a description of your most significant papers and software packages with an explanation of your own contributions to them. Only those applicants selected for further consideration will receive a response.

Undergraduate research opportunity

Ideal for a fourth-year project or summer internship

THE EDGE. Acquire a statistical bioinformatics skill set by developing novel scientific software in the frontiers of post-genomic biology for high impact on medical science.
THE LAB. Scientific breakthroughs from genome-sequencing projects brought the realization that reliable interpretation of the resulting information makes unprecedented demands for contemporaneous advances in computation and mathematical modeling. As the complexity of genomic data sets drives innovative statistics research, the new Statistical Machine Learning in Functional Genomics (Statomics) Lab of the Ottawa Institute of Systems Biology aims to develop and apply novel methodology and algorithms to solve current problems in analyzing gene-expression, proteomics, metabolomics, SNP, ChIP-chip, and/or clinical data. The lab is presently targeting the inference of degrees of differential gene expression and improvements in the repeatability of microarray results and will attack similar statistics and machine learning challenges of importance to functional genomics.
THE STUDENT. Learn to analyze genomics data with newly created statistical methods. Make breakthrough bioinformatics software accessible worldwide by improving the usability and functionality of the lab’s data analysis code and by adding documentation. Providing scientists with these reliable biostatistical tools can advance medical research by improving the accuracy of conclusions drawn from genomics and clinical data.

Send your cover letter and CV or resume, including your GPA, to dbickel0@uottawa.ca (without the zero).